Aspirin use cuts risk of digestive tract cancers by 20-40 percent
Regular aspirin use reduces the risk of digestive tract cancer by 20 to 40 percent, according to findings published on Thursday that bolster growing evidence the common analgesic can help prevent the disease. A review of 113 recent studies covering more than 210,000 patients showed that bowel cancer risk dropped 27 percent, esophageal cancer by 33 percent, stomach cancer by 36 percent, and gastric cardia - where the stomach connects to the wind pipe - cancer by 39 percent.
Regular use of aspirin reduces the risk of gastrointestinal cancer by 20 to 40 per cent, according to Thursday's findings that bolstering evidence of common analgesics can help prevent the disease. A review of 113 recent studies involving more than 210,000 patients showed that the risk of intestinal cancer had decreased by 27 per cent, esophageal cancer by 33 per cent, Magic cancer by 36% and gastric cardia-where the stomach is connected to the wind pipe-cancer by 39%.
For pancreatic cancer, which is almost always fatal, there was a nearly 25 percent reduced risk after five years among people who used aspirin compared to those who did not, researchers reported in Annals of Oncology.
In the case of pancreatic cancer, which is almost always fatal, there was a nearly 25% reduction in risk after five years among people who used aspirin compared to those who did not, researchers reported in Annals of Oncology.
"These findings suggest there's a beneficial effect of aspirin in the prevention of bowel and other cancers of the digestive tract," said senior author Carlos la Vecchia, a professor of epidemiology at the School of Medicine in Milan.
"These findings suggest that aspirin has a beneficial effect on the prevention of intestinal and other cancers of the digestive tract," said Carlos La Vecchia, senior author, professor of epidemiology at the School of Medicine in Milan.
About 175,000 people die from bowel cancer in the European Union every year, about 100,000 of them between the age of 50 and 74.
About 175,000 people die every year from intestinal cancer in the European Union, some 100,000 of them between the ages of 50 and 74.
"If we assume regular use of aspirin increases from 25 to 50 percent in this age group, this would mean 5,000 to 7,000 deaths from bowel cancer, and between 12,000 and 18.000 new cases, could be avoided," La Vecchia said in a statement.
"If we assume regular use of aspirin increases from 25 to 50 percent in this age group, this would mean 5,000 to 7,000 deaths from bowel cancer, and between 12,000 and 18.000 new cases, could be avoided," La Vecchia said in a statement.
Aspirin, which can cause stomach bleeding, is less often recommended or prescribed in patients older than 75.
Aspirin, which can cause bleeding in the stomach, is less often recommended or prescribed in patients over 75 years of age.
A significant body of research over the last decade has established a strong statistical link between long-term aspirin use and a reduced incidence of different kinds of cancer, but the new study is the largest to date focused on the digestive tract, the authors said.
A significant body of research over the last decade has established a strong statistical link between long-term use of aspirin and reduced incidence of different types of cancer, but the new study is the largest to date focused on the digestive tract, the authors said.
Most of the studies examined by La Vecchia and colleagues were designed to test or examine aspirin's capacity to reduce heart disease.
Most of the studies examined by La Vecchia and colleagues were designed to test or examine the ability of aspirin to reduce heart disease.
Regular use of aspirin reduces the risk of gastrointestinal cancer by 20 to 40 per cent, according to Thursday's findings that bolstering evidence of common analgesics can help prevent the disease. A review of 113 recent studies involving more than 210,000 patients showed that the risk of intestinal cancer had decreased by 27 per cent, esophageal cancer by 33 per cent, Magic cancer by 36% and gastric cardia-where the stomach is connected to the wind pipe-cancer by 39%.
For pancreatic cancer, which is almost always fatal, there was a nearly 25 percent reduced risk after five years among people who used aspirin compared to those who did not, researchers reported in Annals of Oncology.
In the case of pancreatic cancer, which is almost always fatal, there was a nearly 25% reduction in risk after five years among people who used aspirin compared to those who did not, researchers reported in Annals of Oncology.
"These findings suggest there's a beneficial effect of aspirin in the prevention of bowel and other cancers of the digestive tract," said senior author Carlos la Vecchia, a professor of epidemiology at the School of Medicine in Milan.
"These findings suggest that aspirin has a beneficial effect on the prevention of intestinal and other cancers of the digestive tract," said Carlos La Vecchia, senior author, professor of epidemiology at the School of Medicine in Milan.
About 175,000 people die from bowel cancer in the European Union every year, about 100,000 of them between the age of 50 and 74.
About 175,000 people die every year from intestinal cancer in the European Union, some 100,000 of them between the ages of 50 and 74.
"If we assume regular use of aspirin increases from 25 to 50 percent in this age group, this would mean 5,000 to 7,000 deaths from bowel cancer, and between 12,000 and 18.000 new cases, could be avoided," La Vecchia said in a statement.
"If we assume regular use of aspirin increases from 25 to 50 percent in this age group, this would mean 5,000 to 7,000 deaths from bowel cancer, and between 12,000 and 18.000 new cases, could be avoided," La Vecchia said in a statement.
Aspirin, which can cause stomach bleeding, is less often recommended or prescribed in patients older than 75.
Aspirin, which can cause bleeding in the stomach, is less often recommended or prescribed in patients over 75 years of age.
A significant body of research over the last decade has established a strong statistical link between long-term aspirin use and a reduced incidence of different kinds of cancer, but the new study is the largest to date focused on the digestive tract, the authors said.
A significant body of research over the last decade has established a strong statistical link between long-term use of aspirin and reduced incidence of different types of cancer, but the new study is the largest to date focused on the digestive tract, the authors said.
Most of the studies examined by La Vecchia and colleagues were designed to test or examine aspirin's capacity to reduce heart disease.
Most of the studies examined by La Vecchia and colleagues were designed to test or examine the ability of aspirin to reduce heart disease.
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